Dual Philosophy in Death Receptor Signalling

Dual Philosophy in Death Receptor Signalling

Tumour necrosis factor (TNF) is the founding member of a cytokine family with important roles in both, physiology and pathological conditions. The two seemingly opposing cellular responses to stimulation by TNF itself are death and induction of pro-inflammatory signalling. TNF and other TNF superfamily (SF) members signal by crosslinking their cognate receptors. These form part of the TNF recep...

Death receptor signalling in central nervous system inflammation and demyelination.

Death receptors (DRs) are members of the tumor necrosis factor receptor (TNF-R) superfamily that are characterised by the presence of a conserved intracellular death domain and are able to trigger a signalling pathway leading to apoptosis. Strong evidence suggests that DRs contribute to the pathology of tissue destructive diseases, including multiple sclerosis (MS), the most common inflammatory...

Review of “ Death and Philosophy ”

The death of costly signalling?

the picture of the life after death in avicenna’s philosophy

the aim of this article is to examine avicenna’s theory of the immortality of human soul. avicenna believes in immortality of the soul and resurrection of the body but he engages in a philosophical investigation about the former not the latter. according to his view, religion has talked of resurrection of the body in detail. the picture he presented of the immortality of the soul, viz spiritual...